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Kwiatkowski TJ, Jr., Bosco D, LaClerc AL, Tamrazian E, Van den Berg CR, Russ C, Davis A, Gilchrist J, Kasarskis EJ, Munsat T, Rouleau GA, Hosler BA, Cortelli P, de Jong PJ, Yoshinaga Y, Haines JL, Pericak-Vance MA, Yan J, Siddique T, McKenna-Yasek D, Sapp PC, Horvitz HR, Landers JE, Brown RH, Jr. (2009) Mutations in the FUS/TLS Gene on Chromosome Cause Familial Amyotrohic Lateral Sclerosis. Science VOL 323, ISSUE 5917 Publications (submitted)
Saeed M, Yang Y, Deng HX, Hung WY, Siddique N, Dellefave L, Gellera C, Andersen P, Siddique T. Age and founder effect of SOD1 A4V mutation causing ALS. Submitted to Neurology. Publications (preparation) Deng HX, Zhai H, Fu, R, DelCanto M, Mugnani E, Siddique T. Alsin knockout causes motoric impairment in mice but does not affect onset of symptoms in SOD1 mice: two separate neurodegenerative pathway.
Tsaousidou MK, Ouahchi K, Warner TT, Yang Y, Simpson MA, Laing NG, Wilkinson Pa, Madrid RE, Patel H, Hentati F, Patton MA, Hentati A, Lamont PJ, Siddique T, Crosby AH. (2008) Sequence alterations within CYP7B1 implicate defective cholesterol homeostasis in motor-neuron degeneration. American Journal of Human Genetics 82(2):510-515.
Deng HX, Jiang H, Fu R, Zhai H, Shi Y Liu e, Hirano M, DalCanto MC, Siddique T. (2008) Moleular dissection of ALS-associated toxicity of SOD1 in transgenic mice using an exon-fusion approach. Human Mol Genetics 17(15):2310-2319. Lambrechts D, Poesen K, Robberecht W, Fernandez-Santiago R, Al-Chalabi A, Del Bo R, Wj Van Vught P, Carmeliet P, Thijs V, Siddique T. (2008) Meta-analysis of VEGF variations in ALS: increased susceptibility in male carriers of the -2578AA genotype. J Med Genet 18 (online) Siddique T, Leimpeter A, Van Den Eeden SK. (2008) Regional north American annual meeting of the World Federation of Neurology-research group on neuroepidemiology. Neuroepidemiology. 30(2):129-136. Siddique T. (2008) What is missing in ALS? Lancet Neurology 7(4):289-290. Frutiger K, Lukas TJ, Gorrie G, Ajroud-Driss S, Siddique T. (2008) Gender difference in levels of Cu/Zn-Superoxide dismutase (SOD1) in cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis 9:184-187. Ajroud-Driss S, Rusit R, , Siddique T, Hain TC. Oculomotor involvement in myotonic dystrophy type 2. (2008) Muscle Nerve 38(4):1326-1329.
Mackenzie IRA, Bigio EH, Ince PG, Geser F, Neumann M, Cairns NJ, Kwong LK, Forman MS, Ravits J, Stewart H, Eisen A, McClusky L, Kretzschmar HA, Monoranu CM, Highley JR, Kirby J, Siddique T, Shaw PJ, Lee VMY, Trojanowski JQ. (2007) Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. Ann Neurol 61(5):427-434.
Mishra M, Paunesku T, Woloschak GE, Siddique T, Zhu L, Lin S, Greco K, Bigio EH. (2007) Gene expression analysis of frontotemporal lobar degeneration of the motor neuron disease type with ubiquitinated inclusions. Acta Neuropathologica 114(1):81-94. Ajroud-Driss S, Khan H, Siddique N, Hung WY, Sufit R, Heller S, Armstrong J, Casey P, Siddique T, Lukas TJ. (2007) Riluzole metabolism and CYP1A1/2 polymorphisms in patients with ALS. Accepted Amyotrophic Lateral Sclerosis 8(5)305-309. Deng, HX, Zhai H, Fu R, Shi Y, Gorrie GH, Yang Y, Liu E, DalCanto MC, Mugnaini E, Siddique T. (2007) Distal axonopathy in an alsin-deficient mouse model. Human Molecular Genetics 16(23):2911-2920. Wang L, Sharma K, Deng HX, Siddique T, Grisotti G, Liu E, Roos RP. (2007) Restricted expression of mutant SOD1 in spinal motor neurons and interneurons induces motor neuron pathology. Neurobiology of Disease. 29(3):400-408. Siddique T. (2007) Neurobiology of Mental Health. Pakistan Journal of Neurological Sciences (Pak J Neruol Sci.) 2(4):230-234.
Deng HX, Shi Y, Furukawa, Y, Zhai H, Fu R, Liu E, Gorrie G, Khan MS, Hung, WY, Bigio EH, Lukas T, Dal Canto MC, O’Halloran T, Siddique T. (2006) Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria. PNAS 103: 7142-7147.
Furukawa Y, Fu R, Deng HX, Siddique T, and O’Halloran TV. (2006) From the Cover: Disulfide cross-linked protein represents a significant fraction of ALS-associated Cu, Zn-superoxide dismutase aggregates in spinal cords of model mice. PNAS 103:7148-7153 Gul A, Hassan MJ, Mahmood S, Chen W, Rahmani S, Naseer MI, Dellefave L, Muhammad N, Rafiq MA, Ansar M, Chishti MS, Ali G, Siddique T, Ahmad W. (2006) Genetic studies of autosomal recessive primary micorcephaly in 33 Pakistani families: Novel sequence variants in ASPM gene. Neurogenetics 7:105-110. Vance C, Al-Chalabi A, Ruddy D, Smith DN, HuX, Sreedharan J, Siddique T, Schelhassa H, Kusters B, Troost D, Baas F, de Jong V, Shaw CE. (2006) Famililial amyotrohic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13.2-21.3. Brain 129(pt 4):868-878. Chen W, Saeed M, Mao H, Siddique N, Delelfave L, Hung WY, Deng HX, Sufit R, Heller S, haines J, Pericak-Vance MA, Siddique T. (2006) Lack of association of VEGF promoter polymorphisms with sporadic amyotrophic lateral sclerosis. Neurology 67(3):508-510. Saeed M, Siddique N, Hung WY, Usacheva E, Liu E, Sufit RL, Heller SL, Haines JL, Pericak-Vance MA, Siddique T. (2006) Paraoxonase cluster polymorphisms are associated with sporadic amyotrophic lateral sclerosis. Neurology 67(5):771-776. Lukas TJ, Luo WW, Mao H, Cole N, Siddique T. (2006) Informatics-assisted protein profiling in a transgenic mouse model of amyotrophic lateral sclerosis. Mol Cell Proteomics 5(7):1233-1244.
Faiyaz-Ul-Haque M, Zaidi SHE, King L, Haque S, Patel M, Ahmad M, Siddique T, Ahmad W, Tsui LC, Cohn D. (2005) Fine mapping of the X-linked split-hand/split-foot malformation (SHFM2) locus to a 5.1-Mb region on Xq26.3 and analysis of candidate genes. Clin Genet 67(1):93-97.
Kuo JJ, Siddique T, Fu R, Heckman CJ. (2005) Increased persistent Na+ current and its effect on excitability in motoneurones cultured from mutant SOD1 mice. J. Physiology Li X, Rowland LP, Mitsumoto H, Przedkorski S, Bird TD, Schellenberg GD, Peskind E, Johnson N, Siddique T, Mesulam MM, Weintraub S, Mastrianni JA. (2005) Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia. Ann Neurol 58:858-864.
Kuo JJ, Schonewille M, Siddique T, Schults AN, Fu R, Bar PR, Anelli R, Heckman CJ, Kroese AB. (2004) Hyperexcitability of cultured spinal motoneurons from presymptomatic ALS mice. J Neurophsiol 91:571-575.
Henkel JS, Engelhardt JI, Siklós L, Simpson EP, Kim SH, Pan T, Goodman JC, Siddique T, Beers DR, Appel SH. (2004) Presence of Dendritic Cells, MCP-1 and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue. Ann Neuro 545:221-235. Bigio EH, Johnson NA, Rademaker AW, Fung BB, Messulam MM, Siddique N, Dellefave L, Caliendo J, Freeman S, Siddique T. (2004) Neuronal ubiquitinated intranuclear inclusions in familial and non-familial frontotemporal dementia of the motor neuron disease type associate with amyotrophic lateral sclerosis. J Neuropath and Exper Neuro. 63(8):801-811. Morris HR, Steele JC, Crook R, Wavrant de-Vriez F, Onstead-Cardina L, Gwinn-Hardy K, Wood NW, Farrer M, Lees AJ, McGeer PL, Siddique T, Hardy J, Perez-Tur J. (2004) Genome wide analysis of the parkinsonism-dementia complex of Guam. Arch Neurol. 61(12)1889-18897. Li YJ, Pericak-Vance MA, Haines JL, Siddique N, McKenna-Yasek D, Hung WY, Sapp P, Allen CI, Chen W, Hosler B, Saunders AM, Dellefave L, Brown Jr, RH, Siddique T. (2004) Apolipoprotein E is associated with age at onset of Amyotrophic Lateral Sclerosis. Neurogenetics 5:209-213.
Mesulam M, Siddique T, and Cohen B. (2003) Cholinergic denervation in a pure multi-infarct state: Lessons from CADASIL. Neurology 60(7):1183-1185.
Aksoy H, Dean G, Elian M, Deng HX, Deng G, Juneja T, Storey E, McKinlay Gardner RJ, Jacob RB, Laing NG, Siddique T. (2003) A4T mutations in the SOD-1 gene causing Familial Amyotrophic Lateral Sclerosis. Neuroepidemiology 22:235-238. Sapp PC, Hosler BA, McKenna-Yasek D, Chin W, Gann A, Genise H, Gorenstein J, Huang M, Sailer W, Scheffler M, Valesky M, Haines JL, Pericak-Vance M, Siddique T, Horvitz HR, Brown, RH. (2003) Identification of two novel loci for dominantly inherited familial amyotrophic lateral sclerosis (the Contribution). Am J Hum Genet. 73(2):397-403. Ruddy DM, Parton MJ, Al-Chalabi A, Lewis C, Leigh PN, Powell JF, Siddique T, Meyjes EP, Baas F, De Jong V, Shaw CE. (2003) Two families with familial amyotrophic lateral sclerosis are linked to a novel locus on chromosome 16q. Am J Hum Genet 73:390-396. Rezania K, Yan J, Dellefave L, Deng HX, Siddique N, Pascuzzi RT, Siddique T, Roos RP. (2003) A rare Cu/Zn superoxide dismutase mutation causing familial amyotrophic lateral sclerosis with variable age of onset, incomplete penetrance and a sensory neuropoathy. Amyotroph Lateral Scler Other Motor Neuron Disord 4(3):162-166. El Euch-Fayache G, Lalani I, Amouri R, Turki I, Ouahchi K, Hung WY, Belal S, Siddique T, Hentati F. (2003) Phenotypic features and genetic findings in Sascin-related autosmal recessive ataxia in Tunisia. Arch Neurol. 60:982-988.
Faiyaz-Ul-Haque M, Ahmad W, Wahab A, Haque S, Azim AC, Zaidi SH, Teebi AS, Ahmad M, Chon DH, Siddique T, Tsui LC (2002) Frameshift mutation in the cartilage-derived morphogenetic protein 1 (CDMP1) gene and severe acromesomelic chondrodysplasia resembling Grebe-type chondrodysplasia. Am J Med Genet. 111(1):31-37.
Jonsson PA, Bäckstrand Å, Andersen PM, Jacobsson J, Parton M, Shaw C, Swingler R, Shaw PJ, Robberecht W, Ludolpph AC, Siddique T, Skvortsova VI, Marklund SL. (2002) CuZn-Superoxide dismutase in D90A heterozygotes from recessive and dominant ALS pedigrees. Neurobiology of Disease 10:327-333.
Yang Y, Hentati A, Deng HX, Dabbagh O, Sasaki T, Hirano M, Hung WY, Ouahchi K, Yan J, Azim AC, Cole N, Gascon G, Yagmour A, Ben-Hamida M, Pericak-Vance M, Hentati F, and Siddique T. (2001) The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis. Nature Genetics 29:160-165.
Cox PR, Siddique T, and Zoghbi Huda. (2001) Genomic organization of Tropomodulins 2 and 4 and unusual intergenic and intraexonic splicing of YL-1 and Tropomodulin 4. BMC Genomics 2:7. Domitrz I, Jedrzejowska M, Lipowska M, Siddique T and Kwieciński H. (2001) Choroba Kennedy ‘ego: ekspansja trójki nukleotydowej CAG. Neuro. Neurochir. Pol. 35(suppl 1):107-114.
Gaudette M, Hirano M, and Siddique T. (2000) Current status of SOD1 mutations in familial amyotrophic lateral sclerosis. Amyotrohpic Lateral Sclerosis and Other Motor Neuron Diseases, 1(2):83-89.
Hosler BA, Siddique T, Sapp PC, Sailor W, Huang MC, Hossain A, Daube JR, Nance M, Fan C, Kaplan J, Hung WY, McKenna-Yasek D, Haines JL, Pericak-Vance MA, Horvitz HR, and Brown, Jr, RH. (2000) Linkage of familial amyotrophic lateral sclerosis with fronto-temporal dementia (ALS-FTD) to chromosome 9q21-q22. JAMA 284(13):1664-1669. Hentati A, Deng HX, Hong Zhai H, Chen W, Yang Y, Hung WY, Azim AC, Bohlega S, Tandan R, Warner C, Laing NG, Cambi F, Gascon G, Mitsumoto H, Salazar-Grueso EF, Boustany RM, Phillips JP, Powell BR, Ben Hamida M, Hentati F, and Siddique T. (2000) Novel mutations in spastin, the gene for hereditary spastic paraplegia on chromosome 2p (SPG4), and absence of correlation between mutation and age at onset of symptoms. Neurology 55:1388-1390. Deng HX and Siddique T. (2000) Transgenic mouse models and human neurodegenerative disorders. Archives of Neurology 57(12)P1695-1702. Ahmed MS, Hung WY, Zu JS, Hockberger P, and Siddique T. (2000) Increased reactive oxygen species in familial amyotrophic lateral sclerosis with mutations in SOD1. J Neurological Sciences, 176:88-94. Hirano M, Hung WY, Cole N, Azim AC, Deng HX, and Siddique T. (2000) Multiple transcripts of the human Cu,Zn superoxide dismutase gene. Biochem Biophysical Res Commun 276(1):52-56.
Pérez-Tur J, Buée L, Morris HR, Waring SC, Onstead L, Wavrant-De Vrièze, Crook R, Buée-Scherrer V, Hof PR, Petersen RC, McGeer PL, Delacourte A, Hutton M, Siddique T, Ahlskog JE, Hardy J, and Steele JC. (1999) Neurodegenerative diseases of Guam: Analysis of TAU. Neurology 53:411-413.
Siddique T, Pericak-Vance MA, Caliendo J, Hong ST, Hung WY, Kaplan J, McKenna-Yasek D, Rimmler JB, Sapp P, Saunders AM, Scott WK, Siddique N, Haines JL and Brown RH. (1998) Lack of Association between Apolipoprotein E (APOE) and sporadic amyotrophic lateral sclerosis (ALS). Neurogenetics 1:213-216.
Siklós L, Engelhardt JI, Alexianu ME, Gurney ME, Siddique T, and Appel SH. (1998) Intracellular calcium parallels motoneuron degeneration in SOD-1 mutant mice. Journal of Neuropathy and Experimental Neurology 57(6)571-587. Hentati A, Ouahchi K, Pericak-Vance MA, Nijhawan D, Ahmad A, Yang Y, Rimmler J, Hung WY, Schlotter B, Ahmed A, Ben Hamida M, Hentati F and Siddique T. (1998) Linkage of a commoner form of recessive amyotrophic lateral sclerosis to chromosome 15q15-q22 markers. Neurogenetics 2(1):55-60. Al-Chalabi A, Andersen PM, Chioza B, Shaw C, Sham PC, Robberecht W, Matthijs G, Camu W, Marklund SL, Forsgren L, Rouleau G, Laing NG, Hurse PV, Siddique T, Leigh PN, and Powell JF. (1998) Recessive amyotrophic lateral sclerosis families with the D90A SOD1 mutation share a common founder: evidence for a linked protective factor. Human Mol Genetics 7(13):2045-2050.
Kostic V, Gurney ME, Deng HX, Siddique T, Epstein CJ and Przedborski S. (1997) Midbrain dopaminergic neuronal degeneration in a transgenic mouse model of familial amyotrophic lateral sclerosis. Annals of Neurology 41:497-504.
Isozumi K, DeLong R, Kaplan J, Hung WY and Siddique T. (1997) Exclusion of the expansion of CAG/CTG repeats at thirteen loci on chromosome 12 as a candidate genetic mutation in scapuloperoneal spinal muscular atrophy with anticipation. Human Genetics 99:701-703. Zu JS, Deng HX, Lo TP, Mitsumoto H, Ahmed MS, Hung WY, Cai ZJ, Tainer JA and Siddique T. (1997) Exon 5 encoded domain is not required for the toxic function of mutant SOD1 but essential for the dismutase activity: Identification and characterization of two new SOD1 mutations associated with familial amyotrophic lateral sclerosis. Neurogenetics 1:63-70. Xu L, Deng HX, Xia JH, Yang Y, Fan CH, Hung WY and Siddique T. (1997) Assignment of SATB1 to human chromosome band 3p23 by in situ hybridization. Cytogenet Cell Genet 77:205-206. Juneja T, Dave S, Pericak-Vance MA and Siddique T. (1997) Prognosis in familial amyotrophic lateral sclerosis: progression and survival in patients with glu100gly and ala4val mutations in Cu,Zn superoxide dismutase. Neurology 48:55-57. Ahmed MS, Afsar S, Hentati A, Ahmad A, Pasha J, Juneja T, Hung WY, Ahmad A, Choudhri AN, Saya S and Siddique T. (1997) A novel mutation in 27-Hydroxylase gene of a Pakistani family with autosomal recessive Cerebrotendinous Xanthomatosis (CTX). Neurology 48:258-260.
Hentati A, Deng HX, Hung WY, Ahmed S, Nayer M, Ahmed MS, He X, Tim R, Stumpf DA and Siddique T. (1996) The human a-tocopherol transfer protein: gene structure and mutations in familial vitamin E deficiency. Annals of Neurology 39:295-300.
Shibata N, Hirano A, Kobayashi M, Siddique T, Kato T and Asayama K. (1996) Intense superoxide dismutase-1immunoreactivity in intracytoplasmic hyaline inclusion of familial ALS with posterior column involvement. J of Neuropathology and Experimental Neurology 55(4):481-490. Isozumi K, DeLong R, Kaplan J, Deng HX, Iqbal Z, Hung WY, Wilhelmsen KC, Hentati A, Pericak-Vance MA and Siddique T. (1996) Linkage of scapuloperoneal spinal muscular atrophy to chromosome 12q24.1-q24.31. Human Molecular Genetics 5(9): 1377-1382. Bird T, Cambi F, Dube MP, Figlewicz DA, Fink JK, Haines JL, Heiman-Patterson T, Hentati A, Pericak-Vance MA, Raskind W, Rouleau GA and Siddique T. (1996) Hereditary spastic paraplegia: Advances in genetic research. Neurology 46(6):1507. Siddique T and Deng HX. (1996) Genetics of amyotrophic lateral sclerosis. Human Molecular Genetics 5(13):1465-1470. Siddique T. and Hentati A. (1996) Familial amyotrophic lateral sclerosis. Clinical Neuroscience 3:338-347. Siddique T. (Guest ed) Clinical Neuroscience: Motor Neuron Disease. John Wiley & Sons, Inc. New York, NY. 1996 3(6) 323-395.
Deng HX, Tainer JA, Mitsumoto H, Ohnishi A, He X, Hung WY, Zhao Y, Juneja T, Hentati A and Siddique T. (1995) Two novel SOD1 mutations in patients with familial amyotrophic lateral sclerosis. Human Mol Genetics 4(6):113-1116.
Sjalander A, Beckman G, Deng HX, Iqbal Z, Tainer JA and Siddique T. (1995) The D90A mutation results in a polymorphism of Cu,Zn superoxide dismutase that is prevalent in Northern Sweden and Finland. Human Mol Genetics 4(6):1105-1108. Gascon GG, Chavis P, Yaghmour A, Stigsby B, Shums A, Ozand P and Siddique T. (1995) Familial childhood primary lateral sclerosis with associated gaze paresis. Neuropediatrics 26:313-319.
Merette C, Brzustowicz LM, Daniels RJ, Davies KE, Gilliam TC, Melki J, Munnich A, Pericak-Vance MA, Siddique T, Voosen B, Wirth B and Ott J. (1994) An investigation of genetic heterogeneity and linkage disequilibrium with 161 families with spinal muscular atrophy. Genomics 21(1):27-33.
Hentati A, Bejaoui K, Pericak-Vance MA, Hentati F, Hung WY, Figlewicz DA, Ben-Hamida C, Ben-Hamida M, Brown Jr. RH and Siddique T. (1994) Linkage of recessive familial amyotrophic lateral sclerosis (ALS2) to chromosome 2q33-q35. Nature Genetics 7(3):425-428. Gurney ME, Pu H, Chiu AY, Dal Canto MC, Polchow CY, Alexander DD, Caliendo J, Hentati A, Kwon YW, Deng HX, Chen W, Zhai P, Sufit RL and Siddique T. (1994) Motor neuron degeneration in mice expressing a human Cu, Zn superoxide dismutase mutation. Science 264:1772-1775. Hentati A, Pericak-Vance MA, Hung WY, Balal S, Laing N, Hentati F, Ben Hamida M and Siddique T. (1994) Linkage of pure autosomal recessive familial spastic paraplegia to chromosome 8 markers and evidence of genetic locus heterogeneity. Human Mol Genetics 3(8):1263-1267. Hentati A, Pericak-Vance MA, Lennon F, Wasserman B, Hentati F, Juneja T, Angrist MH, Hung WY, Boustany RM, Bohlega S, Iqbal Z, Huether CH, Ben Hamida M and Siddique T. (1994) Linkage of a locus for autosomal dominant familial spastic paraplegia to chromosome 2p markers. Human Mol Genetics 3(10):1867-1871.
Rosen DR, Siddique T, Patterson D, Figlewicz A, Sapp P, Hentati A, Donaldson D, Goto J, O'Regan JP, Deng HG et al. (1993) Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature, 362:59-62.
Deng HX, Hentati A, Tainer J, Iqbal Z, Cayabyab A, Hung WY, Getzoff ED, Hu P, Herzfeldt B, Roos RP, Warner C, Deng G, Soriano E, Smyth C, Parge HE, Ahmed A, Roses AD, Hallewell R, Pericak-Vance MA and Siddique T. (1993) Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase. Science 261:1047-1051.
Hentati A, Hu P, Asgharzadeh S and Siddique T. (1992) Dinucleotide repeat polymorphism at the human erythroid alpha spectrin (SPTA1) locus. Human Molecular Genetics 1(3):218.
Appelbaum JS, Roos RP, Salazar-Grueso EF, Buchman A, Iannaccone S, Glantz R, Siddique T and Maselli R. (1992) Intrafamilial heterogeneity in hereditary motor neuron disease. Neurology 42(8):1488-1492. DeLong R and Siddique T. (1992) A large New England kindred with autosomal dominant neurogenic scapuloperoneal amyotrophy with unique features. Archives of Neurology 49(9):905-908.
Alberts MJ, Kandt RS, Pericak-Vance MA, Bebout J, Speer MC, Siddique T, Yamaoka L, Hung WY, Gaskell PC and Roses AD. (1991) MSP1 RFLP for microtubule associated protein-2 (MAP2). Nucleic Acids Research 19(4):960.
Walker AP, Collins FS, Siddique T, Yamaoka LH, Herbstreith MH, Pericak-Vance MA, Secore SL, Hung WY, Goate AM, Hardy JA, Patterson D, Roses AD and Bartlett RJ. (1991) D21S194 a jump clone from D21S16. Nucleic Acids Research 18;7:1931. Siddique T, Figlewicz DA, Pericak-Vance MA, Haines J, Rouleau G, Jeffers A, Sapp P, Hung WY, Bebout J, McKenna-Yasek D, Deng G, Horvitz R, Gusella J, Brown Jr R, Roses AD and Collaborators. (1991) Linkage of a gene causing amyotrophic lateral sclerosis and evidence of genetic-locus heterogeneity. The New England Journal of Medicine 324(20):1381-1384. Wolf HK, Crain BJ and Siddique T. (1991) Degeneration of the substantia nigra in familial amyotrophic lateral slerosis (FALS). Clinical Neuropathology 10(6):291-296. Siddique T and Brown Jr. R. (1991) Genetic basis of familial amyotrophic lateral sclerosis. The New England Journal of Medicine 325(19):1382-1383. (Reply to letter). Secore SL, Walker AP, Herbstreith MH, Siddique T, Jeffers AJ, DeShields TR, Yamaoka LH, Pericak-Vance MA, Hung WY, Roses AD and Bartlett RJ. (1991) A 3-Allele StuI polymorphism on chromosome 3p14.1-14.2. Nucleic Acids Research 19(22):6349.
Grenningloh G, Schmieden V, Schofield PR, Seeburg PH, Siddique T, Mohandas TK, Becker CM and Betz H. (1990) Alpha subunit variants of the human glycine receptor: Primary structures, functional expression and chromosomal localization of the corresponding genes. The EMBO Journal 3:771-776.
Siddique T, Phillips K, Betz H, Warner K, Hung WY, Laing N and Roses A. (1989) RFLPs of the gene for the human glycine receptor. Nucleic Acids Research, 17;4:1785.
Siddique T, Pericak-Vance MA, Brooks B, Roos R, Antel J, Munsat TL, Phillips K, Warner K, Hung WY, Speer M, Bias W, Siddique N and Roses AD. (1989) Linkage analysis in familial amyotrophic lateral sclerosis. Neurology, 39:919-925. Siddique T, Roper H, Pericak-Vance MA, Shaw J, Warner K, Hung WY, Phillips K, Lunt P, Cumming WJK and Roses AD. (1989) Linkage analysis in the spinal muscular atrophy form of facioscapulohumeral disease. Journal of Medical Genetics 26:487-489. Sarfarazi M, Upadhyaya M, Padberg G, Pericak-Vance M, Siddique T, Lucotte G and Lunt P. (1989) An exclusion map for facioscapulohumeral (Landouzy Dejerine) disease. Journal of Medical Genetics 26:481-484. Bartlett RJ, Walker AP, Laing NG, Koh J, Secore SL, Speer MC, Pericak-Vance MA, Hung WY, Yamaoka LH, Siddique T, Kandt R and Roses AD. (1989) An inherited deletion at the Duchenne dystrophy locus in a normal male: A second distal deletion of two exons distinguishes the affected sibling. Lancet 1(8636):496-397. Laing NG, Siddique T, Bartlett RJ, Yamaoka LH, Hung W-Y, Pericak-Vance MA and Roses AD. (1989) Duchenne muscular dystrophy: detection of deletion by spectrophotometric densitometry. Clinical Genetics 35:393-398.
Siddique T, McKinney R, Hung W Y, Bartlett RJ, Bruns G, Mohandas TK, Ropers HH, Wilfert C and Roses AD. (1988) The poliovirus sensitivity (PVS) Gene is on chromosome 19q126q13.2. Genomics 3:156-160.
Laing NG, Siddique T, Bartlett RJ, Yamaoka LH, Chen JC, Walker AP, Hung, WY and Roses AD. (1988) RFLP for Duchenne muscular dystrophy cDNA clone 44 1. Nucleic Acids Research 16(14B):7209. Walker AP, Bartlett RJ, Laing NG, Siddique T, Yamaoka LH, Chen JC, Hung, WY and Roses AD. (1988) RFLP for Duchenne muscular dystrophy cDNA Clone 30-2. Nucleic Acids Research, 16(18):9072. Pericak-Vance MA, Yamaoka LH, Haynes CS, Speer MC, Haines JL, Gaskell PC, Hung WY, Clark CM, Heyman AL, Trofatter JA, Eisenmenger JP, Gilbert JR, Lee JE, Alberts MJ, Dawson DV, Bartlett RJ, Earl NL, Siddique T, Vance JM, Conneally PM and Roses AD. (1988) Genetic linkage studies in Alzheimer disease families. Experimental Neurology, 102:271-269. Pericak-Vance MA, Hung WY, Yamaoka L, Haynes C, Bartlett RJ, Vance JM, Lee JE, Siddique T, Gaskell PC, Stajich J and Roses AD. (1988) Systematic gene mapping in man: data management considerations. Australian Paediatric Journal 24:(Suppl) 87-89. Bartlett RJ, Pericak-Vance MA, Koh J, Yamaoka LH, Chen JC, Hung WY, Speer MC, Gilbert JR, Lee JE, Kandt RS, Siddique T, Sirotkin-Roses MJ and Roses AD. (1988) Duchenne muscular dystrophy: High frequency of deletions. Neurology 38:1-4. Siddique T, Bartlett RJ, Pericak-Vance MA, Yamaoka L, Koh J, Chen J, Hung WY, Kandt RS and Roses AD. (1988) Update on the molecular genetics of Duchenne muscular dystrophy. Australian Paediatric Journal 24:(Suppl) 9-14.
Bartlett RJ, Pericak-Vance MA, Lanman JT, Killam AP, Gilbert JR, Stajich JM, Chen JC, Siddique T, Kandt RS, Sirotkin-Roses M and Roses AD. (1987) Prenatal detection of an inherited Duchenne muscular dystrophy deletion allele. Neurology 37:355 356.
Vance JM, Pericak-Vance MA, Bowman M, Payne CS, Fredane L, Siddique T, Roses AD and Massey WE. (1987) Chorea acanthocytosis: A report of three families and implications for genetic counselling. Amer J of Medical Genetics 28:403 410. Koh J, Bartlett RJ, Yamaoka LH, Pericak-Vance MA, Speer MC, Phillips K, Hung WY, Ray PN, Worton RG, Gilbert JR, Lee JE, Siddique T, Kandt RS and Roses AD. (1987) An inherited deletion at the Duchenne dystrophy locus in a normal male. Lancet 2(8568):1154-1155.
Roses AD, Pericak-Vance MA, Yamaoka LH, Herbstreith MH, Bartlett RJ, Siddique T, Hung WY, Rose DA, Mohandas TK. and Bruns G. (1986) A new tightly linked DNA probe for myotonic dystrophy. Neurology 36:1146.
Askanas V, Engel WK, Kwan HH, Reddy NB, Husainy T, Carlo J, Siddique T, Schwartzmann RJ and Hanna CJ. (1985) Autosomal dominant syndrome of lipid neuropathy with normal carnitine: Successful treatment with long chain, fatty acid free diet. Neurology 35(1):66 72.
Engel WK, Siddique T and Nicoloff JT. (1983) Effect on weakness and spasticity in amyotrophic lateral sclerosis of thyrotropin releasing hormone. Lancet 2(8341):73-75.
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